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BSc, MBBS, MRCPsych, MSc, PhD

Consultant Psychiatrist | Senior Lecturer

Dr James MacCabe is an Honorary Consultant Psychiatrist in the Psychosis Service.

He is also a Clinical Lecturer in Psychiatry at the Institute of Psychiatry, King’s College London, Visiting Consultant Psychiatrist to the University of the Arts, London, and Visiting Researcher at the Karolinska Institute, Stockholm.

Background

Dr MacCabe received a Bachelor of Science (BSc) degree in Psychology, before qualifying in medicine at the University of London in 1995. He then completed his basic and higher specialist training in psychiatry at the Bethlem and Maudsley hospitals.

In 2004, he was awarded a Special Training Fellowship in Health of the Population Research, which is awarded jointly by the Medical Research Council and the Department of Health, and delivered in collaboration with the Department of Medical Epidemiology and Biostatistics at Karolinska Institute, Stockholm.

In 2006, he completed a Master of Science (MSc) degree in Epidemiology at the London School of Hygiene and Tropical Medicine, and a Doctor of Philosophy (PhD) degree in Psychiatry in 2008. He was awarded the Morris Markowe Prize for Public Education in Psychiatry (2002) and the Research Prize and Bronze Medal (2006).

Research

Dr MacCabe applies a lifecourse epidemiology approach to psychiatric research. The majority of his work utilises large population databases in Scandinavia to study the causes and consequences of schizophrenia, bipolar disorder and other psychoses at the population level.

He also conducts clinical trials on the Psychosis Unit, adding to the evidence base on treatments for psychosis.

Teaching

Dr MacCabe supervises MSc and PhD students at the Institute of Psychiatry. He teaches on the Neuroscience Master of Science (MSc), Mental Health Studies (MSc) and Psychiatric Research (MSc) courses. He is also a tutor for the Maudsley Forum and Advanced Maudsley Forum, which offers lectures and small-group workshops to selected European psychiatrists.

Publications

Demjaha, A., MacCabe, JH, Murray, RM. Schizophrenia and bipolar disorder: the crucial differences are neurodevelopmental. IN PRESS Annals of Clinical Psychiatry.

MacCabe, JH. Lambe, M., Cnattingius S, Sham PC, David AS, Reichenberg A, Murray RM, Hultman CM. (2009) Excellent school performance at age 16 increases risk of adult bipolar disorder: a national cohort study. IN PRESS Br J Psychiatry.

MacCabe JH, Koupil I, Leon DA. (2009) Reproductive success in patients with psychosis and their unaffected siblings: a study of fertility over two generations in a cohort born 1915-1929 in Uppsala, Sweden. IN PRESS, Psychological Medicine.

Reichenberg A, Mill J, MacCabe JH. (2009) Epigenetics, Genomic Mutations and Cognitive Function. IN PRESS Cognitive neuropsychiatry.

Zanelli, J. MacCabe JH. Toulopoulou T, Rabe-Hesketh S, Walshe M, McDonald CD Murray RM. (2008) Neuropsychological correlates of eye movement abnormalities in schizophrenic patients and their unaffected relatives. J Psychiatry Research IN PRESS.

MacCabe, J.H. (2008) Population-based Cohort Studies on pre-morbid cognitive function in schizophrenia. Epidemiologic Reviews.

Peters, ER, Thornton P, Siksou L., Linney Y., MacCabe, JH. (2008) Specificity and origins of the Jump to conclusion” bias in deluded patients. Brit Jnl Clinical Psychology.

MacCabe JH, Lambe MP, Cnattingius S, Torrång A, Björk C, Sham PC, David AS, Murray RM, Hultman CM. (2008) Scholastic achievement at age 16 and risk of schizophrenia and other non-affective psychoses: a national cohort study. Psychol Med 38(8): 1133-1140.

Reichenberg A, MacCabe JH. (2007) Feeling the pressure: work stress and mental health (Editorial). Psychol Med 31; 1-2.

MacCabe JH, Martinsson L, Lichtenstein P, Nilsson E, Cnattingius S, Murray RM, Hultman C. (2007) Adverse pregnancy outcomes in mothers with affective psychosis. Bipolar Disorders 9(3): 305-309.

MacCabe JH, Sunbaunat K, Bunthoeun P. (2007) Psychiatry in Cambodia: the phoenix rises from the ashes. International Psychiatry 4(2): 37-38.

MacCabe, JH. (2006) Good financial management does not necessarily lead to better services (letter). BMJ. Oct 28;333(7574):920.

Lambe M, Hultman C, Torrang A, MacCabe JH, Cnattingius S. (2006) Maternal Smoking During Pregnancy and School Performance at Age 15. Epidemiology 17(5): 524-530.

Bramon E, Dempster E, Frangou S, McDonald C, Schoenberg P, MacCabe JH, Walshe M, Sham P, Collier D, Murray RM. (2006) Is there an association between the COMT gene and P300 endophenotypes? Eur Psychiatry. Jan;21(1):70-3.

Schulze K, MacCabe JH, Rabe-Hesketh S, Crawford T, Marshall N, Zanelli J, Walshe M, Bramon E, Murray RM, McDonald C. (2006). The relationship between eye movement and brain structural abnormalities in patients with schizophrenia and their unaffected relatives. J Psychiatr Res.40: 589-598.

MacCabe JH, Simon H, Zanelli JW, Walwyn R, McDonald CD, Murray RM. Saccadic distractibility is elevated in schizophrenia patients, but not in their unaffected relatives. Psychol Med. 2005.

Zanelli JW, Simon H, Rabe-Hesketh S, Walshe M, McDonald CD, Murray RM, MacCabe JH. (2005) Eye tracking in schizophrenia: does the antisaccade task measure anything that the smooth pursuit task does not? Psychiatry Research 136, 181-188.

McDonald CD, Bullmore ET, Sham PC, Chitnis X, Suckling J, MacCabe JH, Walshe M, Murray RM. (2005) Regional volume deviations of brain structure in schizophrenia and psychotic bipolar disorder: a computational morphometry study. Br J Psychiatry 186: 369-377.

MacCabe, JH, Travis, M. Clozapine-induced obsessive-compulsive symptoms (letter). (2004) Progress in Neuro-psychopharmacology and biological psychiatry, Progress in Neuropsychopharmacology and Biological Psychiatry 28 (2004) 1209.

MacCabe, JH., Murray, RM. (2004) Intellectual functioning in schizophrenia: a marker of neurodevelopmental damage? Journal of Intellectual Disability Research 48(6): 519-523.

MacCabe, J.H., Aldouri, E., Fahy, T.A., Sham, P.C., Murray, R.M. (2002) Do schizophrenic patients who managed to get to university have a non-neurodevelopmental form of illness? Psychological Medicine, 32: 535–544.

MacCabe, J.H., Marks, I.M., Murray, R.M. (2002) Successful exposure treatment of Clozapine-induced Obsessions and Compulsions: Case Report. (Letter) J Clin Psychiatry 63 (12): 1179 – 1180.

Books

MacCabe JH, O’Daly O, Wright P, McGuffin P, Murray RM. (Eds) Beyond Nature Versus Nurture: Genes, environment and their interaction in Psychiatry. Oxford: Taylor And Francis 2006. (Commended, Mental Health category, BMA Book competition 2007).

Book chapters and miscellaneous publications

Hurlow, J., MacCabe, JH. Paradoxes in creativity and psychiatric conditions. In: Kapur, N., Pascual-Leone, A., Ramachandran, V. The Paradoxical Brain, Cambridge University Press, IN PRESS.

MacCabe, JH, Zanelli, J. (2006) Are eye tracking abnormalities related to susceptibility genes for schizophrenia? In: McDonald, CD, Murray, RM (Eds.) What is Inherited in Schizophrenia and Bipolar Disorder? – The Maudsley Family Study of Psychosis. London: Psychology Press.

MacCabe, JH. (2005) prescribing in pregnancy and breast feeding, In Murray, RM. Goldberg DP. (Eds.) Maudsley Handbook of Practical Psychiatry, 45h edition, Oxford University Press, 2005.

Baddeley A, Morris R, David AS, MacCabe JH. (2005) An ABC introduction to cognition for schizophrenia clinicians. In: Morgan K, Eadbard, J, Murray R. (Eds) Cognition and Schizophrenia: Improving Real Life Function.

MacCabe, JH. (2003) Intelligence and Schizophrenia (Commissioned article). National Association of Primary Care Review, 3(2): 218-220.

MacCabe, JH. (2002) When to refer to Experts, In: Murray, RM. Goldberg DP. (Eds.) Maudsley Handbook of Practical Psychiatry, 4th edition, Oxford University Press, 2002. ISBN 0-19-851609-6.

MacCabe JH. (2000). The Latest Drug Treatments for Schizophrenia. In: The Medical Book, 2000. London: Medilink Press.