Eligibility criteria


  • Male or female
  • 2-18 years old for children and adolescents with treatment resistant neuropsychiatric disorders and 2-25 years old for those with neuropsychiatric symptoms arising in the context of rare diseases such as Rett syndrome
  • Children with a variety of neuropsychiatric disorders, in the context of neuroinflammatory, metabolic, genetic or neurodegenerative disorders and acquired brain injury; psychotropic-induced side-effects and neuropsychiatric aspects in children with terminal illness.
  • Children with complex multiple co-morbid neuropsychiatric and neurodevelopmental disorders such as organic pathology, ADHD, autism spectrum disorders, obsessive compulsive disorder, Tourette’s syndrome or tic disorders, bipolar disorder, depression and psychosis.

1)     CIPPRD provides CLEAR, COMPLETE, CARE programmes for assessment and treatment in three distinct areas:1)     CIPPRD-CLEAR Programme – Consultation-Led Effective Assessment and Recovery (Prevention and Reduction of Inpatient Care) for:

  • Children with multiple and high level neuropsychiatric needs who would otherwise require an admission; or children being considered for an inpatient admission, with the aim of keeping them out of inpatient care
  • Children who have been rejected for admission despite need and require management in the community
  • Children who have not responded adequately to long inpatient admission – we will work with the inpatient team to optimise care

2)     CIPPRD-COMPLETE Programme – Complex Multi-diagnoses Patient-Led Effective Treatment & Empowerment (Multi-comorbid Treatment-Resistant Group) for:

  • Children who have multiple comorbidities and present with severe mental health needs / risks and severe challenging behaviour
  • Children with treatment-resistant disorders, especially in the context of previous failed multiple pharmacological interventions
  • Children where multi-agency co-working is essential to optimize outcomes

3)     CIPPRD-CARE Programme – Comprehensive Assistance for Rare Etiologies (Organic and Rare Disease Group) for:

  • Children with organic conditions and neurometabolic syndromes in the context of neuroinflammatory, genetic or medical disorders who present with neurodegeneration, skills regression or dementia e.g. lysosomal storage disorders such as Hurler’s syndrome, Hunter’s syndrome, Sanfilipo and Gaucher’s disease, Niemann-Pick Type C. We have specific programmes for Rett syndrome and Mucopolysaccharidoses.
  • Children with severe and profound acquired brain injury (including those admitted in Tadworth Children’s Trust for neurorehabilitation)
  • Children with history and high risks of serious medication-related side-effects such as tardive dyskinesia and cardiac complications, and children who need medication to manage psychopathology in medically high-risk groups such as cardiomyopathy and those with organ transplants


  • Two years old and under

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